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For cutting edge AFM research, such as molecular imaging and dynamic force imaging, it is often critical to use probes with specific combinations of resonance frequency and force constants. The Nanonics production technology is capable of producing glass cantilevers with resonance frequencies and force constants which are extremely difficult to achieve with silicon cantilevers.
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Yeast Cells Imaged with an AFM Probe
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Simultaneous NSOM GFP Image |
In addition, glass cantilevers have dynamic response capabilities far beyond those of silicon cantilevers. Response times of 1 micro-second are achievable, three orders of magnitude faster than the best silicon cantilevers. Such response times can monitor a variety of dynamic events including protein conformational dynamics.
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Optical Fiber AFM Probe Specifications
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Tip Diameter
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>10 nm
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Tip Length
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30 µm - 500 µm
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Cantilever Height
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50 µm - 500 µm (Deep Trench probes available)
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Cantilever Length
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300 µm - 1000 µm
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Force Constant
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from below 1N/m to over 10 N/m
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Resonant Frequency
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20-390 kHz
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